Stemcelline Vial – UC Xeno – Free Mesenchymal cells

20 million in 4ml

The majority of MSC applications include the therapy of immune- and inflammation-mediated disorders as well as tissue degradation, with MSCs showing significant promise for the treatment of incurable diseases.

Fetal bovine serum (FBS), a popular supplement for cell growth but also a potential risk for transmission of infections obtained from animals, is a component of conventional MSC cultures.

How are we different?
1. The health and medicine use of the donor is just two factors that affect the quality of MSCs. 
2. The quantity of MSCs recovered from older individuals is often modest since in vivo MSC synthesis declines with age. Therefore, creating a technique that consistently provides high MSCs is crucial for cell therapy.

The possibility of safe usage in human clinical therapy was demonstrated using xeno-free media. A xeno-free medium must be studied before being used for MSC cultures since these xeno-free media have various effects on MSCs.

To find a common cultural setting for all of these MSC sources, we experimented with a commercial xeno-free. The cells’ population doubling times (P2 to P6) and the expression of surface markers were examined.

We found two medium candidates that supported the isolation and culture of UC-MSCs using UC as the main screening. MSCs produced from BM and AD can also grow in these environments. The cells might develop into chondrocyte, adipocyte, and osteoblast/osteocyte lineages.

In order to determine the safety and viability of using UC-MSCs to treat bronchopulmonary dysplasia and chronic obstructive pulmonary disease, we are now undertaking a phase 1 clinical investigation.

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